Gilead Sciences, Inc. Stock Price Targets

Comprehensive analysis of short, mid, and long-term price targets for Gilead Sciences, Inc. (GILD).

Give me a comprehensive price target analysis for Gilead Sciences, Inc. (GILD).

Price target lines drawn

  • Low Target (100): drawn and extended to 2025-11-09 using color #1E90FF
  • Median Target (128): drawn and extended to 2025-11-09 using color #FFA500
  • High Target (145): drawn and extended to 2025-11-09 using color #32CD32

Executive Summary Gilead Sciences (GILD) sits in a mature pharmaceutical franchise with a strong cash position and a solid dividend, but with notable debt and an earnings trajectory that hinges on pipeline performance and product mix. With a current price around 116.74 and a forward multiple trimmed by improved visibility into earnings, the stock offers a measured upside to the analyst mean/median targets while presenting downside risk tied to pipeline outcomes and patent/profit durability. The three price targets (100, 128, 145) provide clear levels to watch as catalysts unfold.

  • Price action stance: trading above the 50-day moving average, with bullish MACD momentum and a mid-range RSI, suggesting modest near-term upside potential.
  • Valuation: trailing P/E ~23x, forward P/E ~15.7x, P/B ~7.4x. Favorable forward multiple vis-a-vis earnings growth expectations, but leverage (debt/EBITDA) remains a consideration.
  • Dividend: 2.67% yield, below the five-year average (3.89%), reflecting a more conservative payout relative to history.

Fundamental Analysis Key metrics (as of today)

MetricValue
Current Price116.74
Market Cap$144.85B
Enterprise Value$165.53B
Trailing P/E23.16x
Forward P/E15.71x
PEG Ration/a
Price to Book7.37x
ROE33.40%
ROA12.62%
Profit Margin21.87%
Gross Margin78.53%
Operating Margin39.16%
Debt to Equity127.34x
Total Cash$6.06B
Total Debt$24.95B
Dividend Yield2.67%
Five-Year Avg Dividend Yield3.89%
Beta0.354

Interpretation:

  • Substantial profitability with robust gross and operating margins. Return metrics imply solid efficiency, but leverage is a notable trait (very high debt-to-equity in context).
  • Cash reserves exist but are modest relative to total debt; net debt ≈ $18.89B (Total Debt − Total Cash).
  • Forward earnings multiple implies potential upside if pipeline milestones materialize, but valuation remains sensitive to earnings visibility and leverage management.
  • Dividend yield is attractive for income-focused investors, but materially below the five-year average.

Earnings Analysis Recent Earnings Summary (selected highlights)

  • Normalized EBITDA across periods shows a range roughly between $3.22B and $3.88B.
  • Net Income from continuing operations (net of minority interests) hovered around $1.25B–$1.96B in the periods shown.
  • Diluted EPS ranged from about $1.04 in the weak quarter to $1.56 in the strongest quarter shown.
  • Total revenue for the periods shown was in the $6.65B–$7.57B band.

Short digest by period (selected figures)

PeriodNormalized EBITDANet Income (Continuing Ops)Diluted EPSTotal Revenue
2025-06-30$3.483B$1.960B$1.56$7.081B
2025-03-31$3.284B$1.315B$1.04$6.667B
2024-12-31$3.224B$1.783B$1.42$7.569B
2024-09-30$3.881B$1.253B$1.00$7.545B
2024-06-30$3.414B$1.614B$1.29$6.953B

Key Earnings Signals

  • Normalized EBITDA has remained solid on a quarterly basis, though the quarterly quarterly EPS swing (e.g., 1.56 in 2025-06-30 vs 1.04 in 2025-03-31) indicates some quarterly volatility, likely reflecting mix, R&D amortization, and unusual items.
  • Net income from continuing operations shows resilience, with mid- to high-single-digit year-over-year improvement on a trailing basis.
  • The mix of "Total Revenue" remains healthy, though there is some quarterly variability, which is typical for a large pharma with multiple franchises and collaboration revenues.

EPS Trend

  • 0q (most recent quarter): Diluted EPS 2.15; 7d/30d/60d/90d trend: 2.152, 2.151, 2.151, 2.163
  • +1q: Diluted EPS 2.10; trend: 2.113, 2.112, 2.112, 2.023
  • 0y: Diluted EPS 8.09; trend: 8.101, 8.099, 8.068, 8.002
  • +1y: Diluted EPS 8.59; trend: 8.598, 8.596, 8.543, 8.545

Interpretation:

  • The company shows a modest quarter-over-quarter lift in the most recent quarter (2.15 vs 2.10). The trailing-12-month EPS sits around the high 8s, reflecting several quarters of solid profitability.
  • The EPS trend indicates a multi-quarter stabilization with modest year-over-year growth in the longer horizon (+1y vs 0y).

EPS Revisions

  • 0q: Up Last7D: 1; Up Last30D: 1; Down Last30D: 1; Down Last7D: 0
  • +1q: Up Last7D: 0; Up Last30D: 0; Down Last30D: 1; Down Last7D: 1
  • 0y: Up Last7D: 2; Up Last30D: 3; Down Last30D: 1; Down Last7D: 0
  • +1y: Up Last7D: 2; Up Last30D: 3; Down Last30D: 1; Down Last7D: 0

Interpretation:

  • Near-term revisions show a small net tilt toward upward revisions in 0q and 0y periods, but the +1q and +1y brackets show more downgrades than upgrades, indicating some negative sentiment in longer horizons.
  • Overall, revisions imply cautious optimism in the near term but a tempered longer-term view.

Technical Analysis (as of the latest data)

  • 50-day Moving Average (latest): around 114.1 (the series ends 2025-10-09 with MA 114.1)
  • Price (latest): 116.74
  • Price vs 50-day MA: Price is slightly above the 50-day MA, a modest bullish signal.
  • RSI (14): latest around 56.6 (mid-range, not overbought)
  • MACD (12,26,9): latest MACD ≈ 0.6; Signal ≈ -0.1, indicating bullish momentum recently
  • Current technical takeaway: The stock is in a constructive setup, trading above the 50-day MA with positive MACD momentum and a mid-range RSI, suggesting potential upside, with modest volatility risk given the stock’s earnings sensitivity and debt considerations.

Analyst Consensus & Price Targets

  • Current Price: 116.74
  • Number of Analysts: 25
  • Target Low / Median / High: 100.0 / 128.0 / 145.0
  • Target Mean: 125.91
  • Market consensus: Modest upside from current levels with a wide target range, reflecting varying views on pipeline risk vs. earnings durability.

Price Target Analysis (Short, Mid, Long-Term) Short-Term (3 months)

  • Target: 128 (Median) or roughly in the 125–129 band
  • Justification:
    • Current price around 116.7 with a forward P/E in the mid-teens, suggesting earnings-driven upside as expectations align with the forward trajectory.
    • Technicals support near-term upside: price above 50-day MA (~114), RSI mid-range, MACD bullish cross dynamics.
    • Analyst sentiment shows near-term upside potential with a median target of 128 and mean near 126.
  • Key drivers:
    • Stabilization of earnings and potential near-term catalysts from pipeline updates or regulatory news.
    • Modest improvement in earnings revisions in the near term.

Mid-Term (12 months)

  • Target: 145 (High) or higher within the 140–145 zone
  • Justification:
    • Forward valuation (~15.7x) suggests continued earnings visibility could push multiples higher if pipeline milestones materialize and margins stabilize or improve.
    • Analyst High target at 145 supports upside potential if near-term momentum sustains, aided by a relatively disciplined debt profile and cash generation.
  • Key drivers:
    • Pipeline milestones across Infectious Diseases and oncology/hyperimmune spaces.
    • Margin expansion from scale and potential cost containment.
    • Continued dividend support in a lower-rate environment.

Long-Term (3+ years)

  • Target (scenario-based): 150–165
  • Justification:
    • Assuming continued earnings resilience, better leverage management, and the achievement of durable revenue growth from late-stage assets or new indications, a longer horizon could warrant multiple expansion above the 12–24 month target.
    • Potential drivers: pipeline progress driving revenue diversification, improved operating leverage, and capital allocation efficiency (buybacks, optionality on strategic partnerships).
  • Risks:
    • Patent cliffs, competitive dynamics, regulatory risk, and slower-than-expected pipeline outcomes could cap upside.
  • Note: The high analyst target present (145) suggests a capped upside scenario in the near term; the longer-term path would depend on actual pipeline success and efficiency gains.

Key Risks & Opportunities

  • Risks:
    • High leverage level (debt/equity) constrains financial flexibility and elevates sensitivity to interest rate changes.
    • Pipeline risk: dependence on remdesivir-related franchises and other antiviral/oncology/HIV products for revenue growth.
    • Patent expiries and competition could pressure pricing and market share.
    • Market headwinds in pharma, including regulatory scrutiny and pricing pressures.
  • Opportunities:
    • Potential upside from new approvals or expanded label indications across antiviral and oncology portfolios.
    • Margin stabilization/expansion with scaling, cost controls, and improved product mix.
    • Share repurchase activity and disciplined capital allocation could support earnings per share over time.

Investment Recommendation

  • View: Hold to modestly accumulate
  • Time Horizon: 12–24 months
  • Expected return potential: roughly 5–15% depending on pipeline milestones, macro environment, and leverage management. Favorable risk-reward if the pipeline milestones come through and the company maintains EBITDA and cash flow strength, with a caveat on balance sheet risk.
  • Rationale: The stock offers a reasonable upside from the current level given forward earnings visibility and a supportive technical setup, but the leverage and pipeline risk keep upside capped short term. A patient holder could benefit from dividend yield and potential M&A or pipeline-driven upside, while being mindful of downside risk around regulatory/patent developments.

Appendix: Numerical Tables (all data as provided or derived) Key Metrics

MetricValue
Current Price116.74
Market Cap$144,851,795,968
Enterprise Value$165,529,419,776
Trailing P/E23.16x
Forward P/E15.71x
PEG Ration/a
Price to Book7.37x
ROE33.40%
ROA12.62%
Profit Margin21.87%
Gross Margin78.53%
Operating Margin39.16%
Debt to Equity127.34x
Total Cash$6.06B
Total Debt$24.95B
Dividend Yield2.67%
Five-Year Avg Dividend Yield3.89%
Beta0.354

Analyst Consensus & Targets

ItemValue
Current Price116.74
Analysts25
Target Low100.0
Target Median128.0
Target High145.0
Target Mean125.9136

Recent Earnings Summary (selected lines)

PeriodNormalized EBITDANet Income (Continuing Ops)Diluted EPSDiluted Avg SharesTotal Revenue
2025-06-303.483B1.960B1.561.255B7.081B
2025-03-313.284B1.315B1.041.259B6.667B
2024-12-313.224B1.783B1.421.259B7.569B
2024-09-303.881B1.253B1.001.254B7.545B
2024-06-303.414B1.614B1.291.251B6.953B

EPS Trend

PeriodCurrent EPS7d Ago30d Ago60d Ago90d Ago
0q Diluted2.149892.151822.151162.130922.16271
+1q Diluted2.096732.112562.112292.127132.02342
0y Diluted8.086748.100628.098878.067638.00189
+1y Diluted8.594078.598198.595828.542508.54452

EPS Revisions (count of changes)

PeriodUp Last 7dUp Last 30dDown Last 30dDown Last 7d
0q1110
+1q0011
0y2310
+1y2310

Technical Indicators (latest)

IndicatorValue (latest)
50-day MA≈ 114.1
Price116.7
RSI (14)≈ 56.6
MACD0.6 (vs Signal -0.1)
InterpretationPrice above MA with bullish momentum; RSI mid-range; modest upside potential with some volatility risk

Notes on Price Targets and Trendlines

  • Horizontal lines drawn:
    • Low Target: 100 (blue)
    • Median Target: 128 (orange)
    • High Target: 145 (green)
  • Extent: All lines extend 30 days into the future from 2025-10-10, reaching 2025-11-09.

Conclusion GILD remains a high-quality, cash-generative pharma name with a solid profitability profile. The forward-looking earnings story is nontrivial but depends on pipeline progress and effective cost/margin management to sustain a favorable multiple. The current setup favors a cautious to modestly constructive stance: upside to the median target (~128) over a few quarters is plausible, with a higher peak near the high target (~145) if pipeline milestones and financials align. The long-run potential (beyond a year) hinges on continued earnings growth and capital allocation that reduces leverage while preserving dividends and buyback support.

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